Confused by speaker wire choices

[PSUfan]

I was planning to run all of the speaker wire for my home theatre in the wall. I have completed lots of research and come to the conclusion that most everyone has some different advice to give. Here are a few of my questions:

1) Should I run the wire for the mains and center in the wall as well? If I did, but used high quality wire would there be sound quality issues.
2) Does anyone have any preferences on brand or vendor they have dealt with that has great prices/product?
3) I would like to use 12 gauge, thoughts?

I have a rotel setup with the 1068 and 1095.

Thanks for the help!
Shane

[KeithM]

1. I don't see how that would make any difference
2. I haven't used any in-wall speaker wire, so I can't help you with that
3. It depends on how long your runs are. 12 gauge is best up to 100 feet( I think), but longer runs will need 10 gauge. I really don't see anyone with that big of a room.